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Proc Natl Acad Sci 104:654659

The corresponding author provided replacement panels from repeat experiments, but in the absence of the original data underlying the published results, these concerns cannot be fully resolved
However, a study of 60 individuals with an immune condition called alopecia areata, which causes hair loss, found they had higher levels of EGF than healthy controls

The big difference here is that cancer research, for example, deals with end of life situations, and any such research can take on higher risks than when dealing with perfectly healthy subjects

Together, interventions that nudge PPP activity, glutamine use, and related shuttles can recalibrate ROS buffering and tip immune responses toward resolution rather than sterile inflammation, without abolishing necessary microdomain redox signaling (Zhou et al

January 10, 2022
