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Clinical studies confirm that up to 500 mg daily is safe for up to 2 months
[DOI] [PubMed] [Google Scholar] 21.Jimnez-Atinzar M, Escribano J, Cabanes J, et al

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Oxidant production by Nox4 has been shown to increase RhoA/ROCK expression in vascular smooth muscle, and other studies show that stimulation of oxidant production in smooth muscle boosts RhoA activity or expression
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Human BPC is found in the gastric juice

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