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Once their journey is complete, these epithelial cells are removed through shedding/apoptosis that does not result in inflammation, normally associated with mass apoptosis

Micronucleus frequency in human lymphocytes is related to plasma vitamin B12 and homocysteine

corroborated by Silverii 2025 RCT meta-analysis (OR 1.55) on a small absolute base

But high blood levels of B12 do not mean symptoms are well treated

see section by Miterko, Beckinghausen, Sillitoe)