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Role of intestinal hif-2 in health and disease

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The pediatric neurologist who evaluated all the EEG recordings (DN) had several decades of experience in pediatric EEG and sleep recording and was blinded to the treatment the child received prior to EEG recording

The loss of elasticity of the lamina cribrosa with aging causes it to lose the ability to recover its normal configuration after normalization of IOP, increasing the prevalence of glaucoma with age ( The effect of this translaminar pressure gradient on axons leads to ischemia/hypoxia damage, blockade of axonal transport and deprivation of neurotrophic factors, ultimately resulting in apoptosis of RGCs (Nickells, 2007