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Thus, NADPH availability is a critical determinant of GSH-dependent defense against ferroptosis 4

Le problme est que les niveaux de glutathion seffondrent dans de nombreuses situations : stress chronique, infections virales (EBV, cytomgalovirus), exposition aux toxines (pesticides, mtaux lourds, pollution), consommation dalcool, prise de paractamol (qui puise directement les rserves hpatiques de glutathion), alimentation pauvre en protines soufres, et vieillissement

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Thus, when ROS production increases to harmful levels, AOXs play a key role in neutralizing them

PEG-MGF attaches a polyethylene glycol polymer to extend the half-life from minutes to hours, converting a local paracrine factor into a systemic agent