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A polyhistidine tag may be placed on either the N- or C-terminus of the protein of interest

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In animal model (aged mice), apelin stimulates autophagy in myofibers, reduces inflammation, and supports muscle repair

Loyer P, Cariou S, Glaise D, Bilodeau M, Baffet G, Guguen-Guillouzo C

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Whole blood, its components (plasma or serum) and circulating cells (peripheral blood lymphocytes, circulating neutrophils, freshly isolated monocytes, red blood cells) are frequently studied in the field of oxidative stress research (Regelmann et al., 1991