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Nanocarriers can be used for accurate tumor targeting, but their limited water solubility impedes the stable storage and poses biosafety risks in clinical translation

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It was also verified that the thiol-alkylating agent NEM prevented AdoMet-induced m dissipation, implying a role for thiol oxidation in the mPT pore opening

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Subsequent vasoconstriction and inflammation ensue, leading to vessel wall remodeling and, finally, to the formation of atherosclerotic lesions as the hallmark of advanced disease