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[0312] Additionally chimeric constructs are provided that expand beyond targeted chemotherapy to immunotherapy by incorporating, for example, providing bispecific antibodies comprising an anti-ALPP/ALPPL2 antibody attached to a second antibody that is capable of recruiting and activating immune system components or attached to a moiety that is a checkpoint inhibitor {e.g., anti- CTLA4 {e.g., comprising an ipilimumab variable region), and/or antibodies directed against PD-L1 {e.g., comprising an nivolumab, or pembrolizumab variable region), and/or antibodies directed against PD-L2

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Role of recombinant human granulocyte colony-stimulating factor in development of cancer-associated venous thromboembolism in lung cancer patients who undergo chemotherapy

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Firstly, cancer cells contain more copper ions, which can react with DSF to form a complex of diethyldithiocarbamate-copper [(Cu (DDC)2 CuET)]