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Metabolic Reprogramming: the Emerging Concept and Associated Therapeutic Strategies

IGF-1 is a 70 amino acid sequence similar to the size and structure of Insulin

The disulfide cross-linked structure provides enhanced stability, preventing premature drug leakage in physiological conditions

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Comprehensive analysis of diverse low-grade neuroepithelial tumors with FGFR1 alterations reveals a distinct molecular signature of rosette-forming glioneuronal tumor

Although -synuclein is frequently implicated in PD pathogenesis, other proteins such as PTEN induced putative kinase 1 (PINK1), Parkin, DJ-1, leucine-rich repeat kinase 2 (LRRK2) have been strongly linked to familial forms of PD 6,7
