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Interestingly, TMAO affects bone homeostasis [13]

consult a health-care practitioner before use if you have a liver or kidney disease or if you have been instructed to follow a low-protein diet

The dosage also varies here depending on the specific application

The behavior exhibited by animals in self-administration experiments is similar to that of drug addicts, and data on characterized behavior patterns such as increases and decreases in lever pressing under certain conditions are used to investigate the mechanisms of physical and psychological dependence 15,16

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Brunzell, JD