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Neuronal death mechanisms and therapeutic strategy in ischemic stroke

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Carmon, K

Moreover, a reduced GSH synthesis could also be a contributory factor for the GSH depletion, as it has been documented in cirrhotic livers [32]

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602 The authors identified a new enzyme, TOT1, to be the responsible enzyme, using a combination of biotransformation, in vitro biochemical characterization, and computational modeling (Figure 74)