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Over time, the body may become accustomed to the medication, making it less effective

In Wilson disease the ATP7B gene is mutated resulting in a malfunctioning copper transporter at the trans-Golgi network

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Duarte, P., Cuadrado, A., & Len, R

Lack of it is common in women with PCOS and has a connection with insulin resistance, ovulatory issues, and infertility

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