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Epileptic Disorders : International Epilepsy Journal with Videotape , 27 , 144155

Like most treatments, vitamin B12 injections carry warnings that patients should be aware of, including: Hereditary Optic Nerve Atrophy: People with early Lebers disease (a hereditary form of optic nerve atrophy) should not receive cyanocobalamin injections, as rapid and severe vision loss has occurred

It is not fully clear if decreased intake is the result of one common eCB/CB1 action, or if several mechanisms are involved

Instead, various transcription factors more likely respond to certain threshold levels of ROS and RNS in a manner that is dependent on both concentration and duration and is likely influenced by the presence of inflammation, DNA damage, metabolic stress, and other factors