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HIV broadly neutralizing antibody precursors to the Apex epitope induced in nonhuman primates
Ephrin-A5 expression was identified on pancreatic CAFs and thought to mediate interaction with EphA receptors on cancer cells, as well as on other CAFs, and to promote collagen synthesis [200]
The absence of allosteric modulation from the RAMP ECD allows the CTR ECD to adopt a conformation that sits further from the receptor TMD than the position observed in the consensus cryo-EM map
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