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Generation of a T cell-dependent ADA response is also a multifactorial process, depending not only on the existence of a potential MHC-II peptide epitope in the mAb, but also on the ability of that epitope to be processed, presented and recognized by T cells

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The primary endpoint was area under the cagrilintide plasma concentration curve from time zero extrapolated to infinity (AUC 0 ) from baseline (day 1) to day 36 (end of study)