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Pietil EA, Gonzalez-Molina J, Moyano-Galceran L, Jamalzadeh S, Zhang K, Lehtinen L, et al

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Finally, by protecting resveratrol from rapid metabolism (particularly glucuronidation and sulfation), the complex reduces the rate of hepatic clearance and prolongs systemic circulation time

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This modification reduces the negative charge on LPS, lowering its affinity for PMs and thus increasing bacterial resistance to these antibiotics