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Mitochondrial energetic and AKT status mediate metabolic effects and apoptosis of metformin in human leukemic cells

The study by Kim et al

The treatment of GBM with a nano drug delivery system would not only improve the pharmacokinetic profile of drugs in the circulation, which may reduce the systemic toxicity and side effects of drugs, but also significantly increase the concentration of drugs

In one of these studies, supplementation with resveratrol at 1 g per day for 45 days resulted in a significant decrease in fasting glucose, insulin, and HbA1C and an increase in insulin sensitivity and HDL cholesterol levels

Wang HJ, Yu WR, Ong HL et al: Predictive factors for a satisfactory treatment outcome with intravesical botulinum toxin a injection in patients with interstitial cystitis/bladder pain syndrome