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The peptide activates extracellular signal-regulated kinase 1/2 (ERK1/2) phosphorylation in a dose-dependent manner, leading to nuclear translocation and activation of transcription factors including c-Fos, c-Jun, and early growth response-1 (Egr-1) that drive expression of genes involved in cell growth, migration, and angiogenesis
BPC-157 (Body Protection Compound-157) is a synthetic peptide derived from a protein found in human gastric juice
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A decrease in the level of this natural antioxidant is one of the earliest biochemical changes seen in patients with the disease and is associated with oxidative stress and neurodegeneration
