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Salidroside, a natural phenylpropanoid glycoside isolated from Rhodiola rosea , has been shown to enhance mitochondrial complex I activity by upregulating and phosphorylating AMPK2, increasing cardiomyocyte tolerance to I/R injury and reducing ferroptosis
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The released retinaldehyde is then reduced to retinol via one of the retinol dehydrogenases
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