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Jaganjac M, Milkovic L, Gegotek A et al (2020) The relevance of pathophysiological alterations in redox signaling of 4-hydroxynonenal for pharmacological therapies of major stress-associated diseases

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Exercise capacity was determined by a single maximal exercise test to voluntary fatigue on a motorized treadmill (Exer 3/6, Columbus Instruments) in females [Young ( n = 10), Old Con ( n = 17), and Old mAb ( n = 22)] and males [Young ( n = 10), Old Con ( n = 9), and Old mAb ( n = 9)]

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This particular chemical composition gives GSH, an important endogenous antioxidant, a high capacity to oxidize or reduce, protecting proteins and other oxidizable compounds from the toxic action of free radicals

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