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J Nutr (1991) 121:35563

Type IV pili binding to CD147/Basigin triggers tyrosine phosphorylation through c-Src and focal adhesion kinase, and EGFR is activated (Slanina et al., 2010, Slanina et al., 2012, Slanina et al., 2014), and acid sphingomyelinase increases ceramide levels on the plasma membrane, forming platforms for the recruitment of host receptors (Simonis et al., 2014

Also, SLC7A11 is negatively modulated by activating transcription factor 3 and p53 at the transcriptional level (Koppula et al., 2021a)

Superoxide, in turn, can react with either superoxide dismutase to form hydrogen peroxide or with NO to form peroxynitrite (Riob et al., 2001)

Both serve distinct purposes

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