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2018) and its activation and/or dimerization with TAAR2 has been linked to peripheral pro-inflammatory outcome (Babusyte et al

[DOI] [PMC free article] [PubMed] [Google Scholar] 63.Saunders D.P., Epstein J.B., Elad S., Allemano J., Bossi P., van de Wetering M.D., Rao N.G., Potting C., Cheng K.K., Freidank A., et al

The final result of these changes results in the continuous increase of hydrogen peroxide (H 2 O 2 ), which restrains the antioxidative enzyme activity leading to the destruction of melanocytes [30]

Thus, the prevalence of PI-positive cells per animal would be a complex product of the rate of PI emergence, the rate of PI disappearance, the rate of nuclear disappearance and the rate of organismal death

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Therefore, the above results suggested that ATF4 could suppress HuOCSC ferroptosis