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Recent reviews report that nanoparticle-in-matrix systems such as lipid or polymeric NPs embedded in gels, films, or solid tablets consistently demonstrate higher bioavailability and prolonged release profiles compared to formulations lacking nanocarriers [141]

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Datar SS, Corsini EM, Mitchell K, Mehran RJ, Rice DC , Sepesi B, Walsh GL, Swisher SG, Roth JA, Vaporicyan A, Hofstetter WL, Loree J, Morris V, Antonoff MB

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Once-Weekly Semaglutide in Adults with Overweight or Obesity (STEP Trials)