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Broad metabolic profiling established a primary role for CBP/p300 in NRF2-dependent accumulation of glutathione and glutathione-related metabolites
Chem Rev 1999;99:2683710
doi: 10.1113/jphysiol.2013.267419, 19
Animal models demonstrated improved neurological outcomes in Parkinsons disease
Synergistic neuroprotective therapies with hypothermia
Consistency with dosing during this establishment phase helps build the foundation for subsequent improvement
