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doi: 10.1038/s41568-019-0235-4 50 WuTDMadireddiSde AlmeidaPEBanchereauRChenYJJChitreASet al

Collaboration between academic institutions, pharmaceutical companies and healthcare providers is essential to facilitate these trials

Moreover, we confirm that MRTX1133 (100 nM) is very specific in inhibiting the KRAS G12D mutant as it has no apparent impact on cells other than SW48 +/G12D on the phosphorylation of ERK and AKT when tested on the full SW48 panel (Appendix Fig

Construction of the inducible reporter strains The plasmid pALC2084, which contains a tetracycline (Tet)-inducible GFP-expressing cassette 67 (kindly provided by Ambrose Cheung, Dartmouth College, Hanover), was first transformed into S

Tordoff, G