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Ion desorption efficiency and internal energy transfer in carbon-based surface-assisted laser desorption/ionization mass spectrometry: desorption mechanism(s) and the design of SALDI substrates

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doi: 10.1089/ars.2012.4645

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The easiness of formation of such covalent bond depends on overall redox potential of environment as well as pH (at low pH the equilibrium is shifted to the reduced, -SH form, under more basic conditions the -SH group is more willing to be oxidized and replaced by -SR, where R is anything except for hydrogen)

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