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10.1016/j.jad.2014.03.041 42

1,25(OH)2D3 induces phosphorylation and nuclear translocation of CEBPB through p38 MAPK activation, which suppresses proliferation by upregulating Notch3 signaling
The condition is relatively common, affecting up to 10% of men at some point in their lifetime, with a higher prevalence seen in specific populations such as after radical prostatectomy (2,3)

He also added 50 years for the development of ceramics in his extension area because he figured the region was a backwater and it would take about that long for ceramics and other cultural artifacts to reach the area

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