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While the absolute [18F]FDG SUV values were comparable or higher than [18F]FSPG, the tumor-to-background SUV ratios were greater with [18F]FSPG than [18F]FDG

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Its characteristics of being highly invasive and undergoing heterogeneous genetic mutation, as well as the presence of the bloodbrain barrier (BBB), have reduced the efficacy of GBM treatment

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