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The future holds great potential for personalized, multi-targeted therapies, innovative delivery systems, and a more comprehensive understanding of TBI, ultimately leading to improved outcomes and quality of life for TBI patients

The degree of TfR1 expression in neurons is proportional to their iron needs

Recent findings indicate that excessive ROS production in HT leads to structural changes in thyroglobulin and thyroid peroxidase, increasing their immunogenicity (Batg et al

15c) [138]

During anemia hepcidin, being the negative regulator of hemopoiesis 36 , blocks the release of Fe from spleen macrophages 37