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Clarke LE, McConnell JC, Sherratt MJ, Derby B, Richardson SM, Hoyland JA

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Several mechanisms of action of NAC have been proposed across different cardiovascular diseases, including enhancement of NO metabolism by supplying free sulfhydryl groups needed for the activation of guanylate cyclase, inhibition of the angiotensin-converting enzyme, prevention of the oxidation of nitrate compounds, reduction of ROS and other free radicals, anti-inflammatory activity, and antiplatelet effects [9, 172, 173]

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