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It was observed that the pretreatment with Tulsi extract before radiation did not affect the radiation-induced cell kill and tumor regression.[] In addition, the investigators also studied the effect of the Ocimum flavanoids on the tumor response to radiation therapy (30 Gy) in B16F1 melanoma and fibrosarcoma bearing mice[] [Figures 3a and b]

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We demonstrated in our previous study that the several analogs of DSIP decreased the toxic effects of the cisplatin cytostatic (reduction of the animal mor- tality, hepatotoxicity, and nephrotoxicity after the administration a half-lethal dose of cisplatin [6]) and could be applicable for an alleviation of toxic effects of cytostatics that were used in oncology

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This enzyme catalyzes the conversion of 4-maleylacetoacetate to 4-fumarylacetoacetate
