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It grabs those fatty acids and carries them into the mitochondria where they are oxidized, or burned, to produce Adenosine Triphosphate (ATP)
Such effects are highly dependent on the nature of the fatty acyl chains, and there is evidence that cholesterol exists in stoichiometric complexes with the saturated fatty acyl groups of sphingomyelin and to a lesser extent of phosphatidylcholine in the membrane microdomains known as rafts, and it has been even suggested that cholesterol may regulate the synthesis of sphingomyelin, especially those molecular species containing very-long-chain fatty acids
Gut microbe-derived metabolites have been increasingly proposed as key factors to explore in cardiovascular health and disease research
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(2022, September 9)
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