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The new study suggests that this may be due to decrease in the rate of carnitine biosynthesis, which may be due to an inadequate iron status in the women

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Outside of confirmed deficiency states, the use of L-carnitine supplements is largely driven by the sports nutrition and weight management market rather than by formal clinical guidance from NICE or the NHS

Immunofluorescence analysis of SREBP2 expression in Huh-7 cells showed that compared with the CON group, the ALC group had significantly reduced SREBP2 levels, and similarly, compared with the TG group, the ALC + TG group had significantly reduced SREBP2 levels (Figures 6F,G)

Discussion As an essential factor in mitochondrial FA -oxidation, L-carnitine has been used to alleviate fat accumulation-related metabolic syndromes in humans and other mammals for decades 8,9,30

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