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Description

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Patients are commonly required to increase dosage amounts as well as the frequency of doses, requiring a dose every 2-3 h, for example [44]

Proc Am Assoc Cancer Res 44:392, 2003

Reduced intestinal blood perfusion, mesenteric ischemia, and decreased bowel movements caused by cirrhosis have appeared to change the normal microenvironment to be less suitable for beneficial populations of Bacteroides and Clostridium , resulting in invasion and colonization of opportunistic pathogens, such as Enterobacteriaceae and Veillonella