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High-dose IV penicillin G is needed for treatment, with the recommended dosage of 18 million to 24 million units per day in divided doses given every 4 hours
To confirm the unbiased groups for the histology-based approach, we also performed a clustering analysis of the integrated object using the eight samples at 0.1, 0.3, and 0.5 resolution (Supplementary Fig

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All validation parameters yielded results within acceptable limits

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