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These fatty acids are the major fuel source for horses at rest and during medium-intensity work

Experiments have shown that female mice lacking Ambra-1 displayed autism-like behavior, supporting the findings of inhibited autophagy in ASD [286]

There is evidence that the synthesis of very-long-chain C24 sphingolipids, mediated by ceramidase isoform 2, is regulated by the availability of long-chain fatty acids, mediated by fatty acid elongase 1 (Reference Ohno, Suto and Yamanaka52)

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Together, all these findings emphasize the essential role of choline availability in macrophage preparedness for an efficient immune response to diverse triggers and reveal that the impact of impaired choline metabolism and utilization on inflammatory molecular pathways is cell- and stimulus-specific

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