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More recent investigations sought to elucidate the properties of specific BSP fractions

Malate then exits the mitochondria and is converted by cytosolic malic enzyme 1 (ME1) into nicotinamide adenine dinucleotide phosphate (NADPH) and pyruvate, with the latter serving as a precursor for lactate synthesis

At the same time, 4-HNE is highly cytotoxic causing protein and DNA damage (199, 211213), affecting autophagy (214, 215), and inducing cell apoptosis (216)

These borderlands are sites of tension, particularly for disadvantaged youth who seek to make good on the promise of the free market (Comaroff and Comaroff 2000, 308)

Cytokine 111:2027