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This probably explains why distal matrix surgery or nail bed surgery have a low potential for scarring as compared to proximal matrix surgery

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It serves as a crucial component in fatty acid transport, stimulates the transfer of long-chain fatty acids into the mitochondria, where they undergo -oxidation to create acetyl-CoA, a precursor for ATP synthesis via the tricarboxylic acid cycle (TCA cycle) [5, 6, 26]

This condition is specifically known as angular cheilitis and is essentially an inflammation of the lips
Several studies indicate that the early lesions occur at the level of the optical nerve, in particular, in the proximity of the head of the optic nerve at the level of the lamina cribrosa