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Glutathione's antioxidant action does have a mild protective effect on melanocytes, the cells responsible for hair pigmentation, but it is not formulated or concentrated enough in typical supplement doses to make a meaningful difference to grey hair on its own

Nicotinamide adenine dinucleotide (NAD+) is a critical metabolite that acts as a cofactor in energy metabolism, and serves as a cosubstrate for non-redox NAD+-dependent enzymes, including sirtuins, CD38 and poly(ADP-ribose) polymerases

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