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First is the antioxidant paradox: chronic antioxidant supplementation can inadvertently protect circulating tumor cells (CTCs) from oxidative stress during metastasis, thereby promoting distant dissemination [203, 312, 313]

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Recent studies have shown that HSCs have unique metabolic characteristics

J Intern Med 265(2):210228 Koga YMDP, Akita YMDP, Nishioka J, Yatsuga S, Povalko N, Tanabe YMDP, Matsuishi T (2005) L-arginine improves the symptoms of stroke-like episodes in MELAS

However, only two pH values were evaluated, so no specific conclusion could be drawn from those studies [25]

10.1523/JNEUROSCI.4129-11.2012 92 KazamaM.KatoY.KakitaA.NoguchiN.UranoY.MasuiK.et al