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Efficacy and safety of vixarelimab, a human monoclonal oncostatin M receptor B Antibody, in moderate-to-severe prurigo nodularis: A randomised, double-blind, placebo-controlled, phase 2a study

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The subjects were randomized to receive glutathione capsules in a dose of 500 mg/day in two divided doses, or placebo for four weeks

Oxidative stress promotes myocardial fibrosis by upregulating KCa3.1 channel expression in AGT-REN double transgenic hypertensive mice

Figure 2 2.2 Dynamic polarization and functional switch of macrophages Macrophages directly recognize pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) via surface pattern recognition receptors (PRRs) and opsonin receptors, internalizing them via receptor-mediated endocytosis