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Current research has not indicated if there is a higher therapeutic dose that is appropriate for cancer patients, although for disease prevention in other medical conditions, such as osteoporosis, a dose of 5 mg/day was recommended

Tailoring a treatment strategy based on injury is critical for optimal recuperation results

doi: 10.1111/j.1600-6143.2006.01485.x

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Furthermore, 4-OH-E undergoes further metabolism to E-3,4-Q, a process that concurrently generates ROS
