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Medications that can induce B6 deficiency or antagonize its actionsuch as isoniazid, cycloserine, hydralazine, and penicillaminemay necessitate supplemental B6 under medical supervision

doi: 10.1186/s12860-018-0172-1 Summary Keywords gut-brain axis, neuropathic pain, migraine mental disorder, schizophrenia, major depressive disorder Citation Riehl L, Frst J, Kress M and Rykalo N (2024) The importance of the gut microbiome and its signals for a healthy nervous system and the multifaceted mechanisms of neuropsychiatric disorders

The study design did not include a control group of post-bariatric patients not using semaglutide for comparison

Agboigba, E

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Tumor necrosis factor- (TNF-) enhances iron uptake and retention in astrocytes and microglia by increasing DMT1 expression, while transforming growth factor-1 (TGF-1) promotes astrocytic iron efflux via FPN1 upregulation (Rathore et al., 2012)