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Abstract The intestinal epithelium acts as the first line of defence against pathogens present in the lumen of the gastrointestinal tract
Miousse, S
Antioxidant capacity in the lung is substantially reduced and oxidative stress can persist long after the cessation of cigarette smoking or an acute exacerbation of COPD owing to continued production of ROS from endogenous sources [9, 12]

Additionally, oxidative stress activates the inflammatory cascade

In: Motulsky, A.G., Bobrow, M., Harper, P.S., Schivver, C
PloS Biol
