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Description

GLUT4glucose transporter 4

Aug 1 2019;104(8):3525-3534

Histamine H Receptor Antagonist (H 2 RA)/Proton Pump Inhibitor (PPI) Induced Vitamin B 12 Depletion Literature suggests that drugs which suppress stomach acid production such as PPIs 159163 and HRAs 164167 interfere with vitamin B 12 absorption, by reducing dietary B12 release from food proteins

In addition to the disruption in iron homeostasis, nuclear receptor coactivator 4-mediated ferritinophagy can lead to iron accumulation and ferroptosis [24]

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