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Gently swirl (do not shake) the Methylcobalamin 10,000 mcg vial around until the solution is clear

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Once mixed, the final solution should be approximately isotonic if given IV (meaning it should contain appropriate solute concentration for safety)

Depletion of Aurora-A co-activators from asynchronous U251 cells, particularly that of BORA, CEP192 and TPX2, led to increased levels of mitotic phosphorylations (PPP1CA-pT320, PRC1-pT481 and Histone-H3-pS10), indicative of delayed mitotic progression (Fig