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This leakage further activates microglia towards the M1 phenotype, promoting release of neurotoxic agents, including TNF- and IL-6 (50)
National Institutes of Health (NIH)

Racine HL, Meadows CA, Ion G, Serrat MA
RMT begins with ligand-receptor binding, which is quickly followed by receptor-mediated endocytosis, delivering the drug carrier attached to the ligand to a specific location
These hormonal alterations, which, except for fT4, are more pronounced in the second and third trimesters, are suggestive of different disrupting effects of phthalates on thyroid function depending on the timing of exposure [101]
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