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doi: 10.1016/S1570-9639(03)00044-X

Increased ROS production leads to disturbances in the balance between oxidation and the antioxidant defense system of the body, causing oxidative stress and this has been observed in cancer cells (Trachootham et al., 2009)

Operating on Stage-IV lung CA: New Frontiers for Thoracic Surgery

It is predicted that the negatively charged carboxylate ion in the -alanine zwitterion can act as a ligand to bind to the positively charged Cu 2+ , Zn 2+ , and/or Fe 2+ ions, facilitating chelation and preventing the catalytic conversion of O2 into ROS, thereby reducing neuronal damage

[DOI] [PubMed] [Google Scholar] 83.Craven L, Alston CL, Taylor RW, Turnbull DM

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