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Shikonin (SHK), a natural compound isolated from Lithospermum erythrorhizon roots, exhibits diverse bioactivities, including antioxidant, anti-inflammatory, and antitumor effects, and functions as a proteasome inhibitor and necroptosis inducer (Guo et al., 2019

Curcumin suppresses epithelial-to-mesenchymal transition of peritoneal mesothelial cells (HMrSV5) through regulation of transforming growth factor-activated kinase 1 (TAK1)

GSTM1-null and GSTT1-null may contribute to the clinical course of patients with type 2 diabetes mellitus (T2DM) (14)
