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Systemic effects less commonly include mild dizziness or lightheadedness (may be copper-related), temporary nausea or headache (typically resolves within hours), mild fatigue (rare, reported with higher doses), and transient flu-like symptoms (very rare, may relate to systemic inflammatory response)

GHK-Cu isnt found in face cream or over-the-counter moisturizer formulations

Safety and effectiveness in pediatric patients have not been established